Can I run Yi-1.5-34B on an NVIDIA B300?

Yes

Its published weights (68.8 GB) fit in the 259 GB an NVIDIA B300 can use, with room for ≈ 4K tokens of context.

Full analysis of Yi-1.5-34B Everything that runs on NVIDIA B300 Get the weights on Hugging Face

hf download 01-ai/Yi-1.5-34B

Files and context on NVIDIA B300

Each file of Yi-1.5-34B (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On NVIDIA B300	Context (16-bit)	Context (8-bit)
As published	68.8 GB	Fits	4K	4K
4-bit (estimate)	19.3 GB	Fits	4K	4K

Yi-1.5-34B on other hardware

NVIDIA B300Yes
NVIDIA H100Yes, just
RTX 5090Probably, at 4-bit
RTX 4090Probably, at 4-bit
RTX 3090Probably, at 4-bit
RTX 5060 Ti 16 GBNo
RTX 3060 12 GBNo
RTX 4060No
Mac with 32 GBProbably, at 4-bit
Mac with 64 GBProbably, at 4-bit
Mac with 128 GBYes

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Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.