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Can I run Qwen3.8-Flash-Next-GGUF on a Mac with 64 GB?

No

Even its smallest file (IQ4_XS, 84.9 GB) is more than a Mac with 64 GB can hold (48.0 GB usable): it needs a Mac with 128 GB.

Full analysis of Qwen3.8-Flash-Next-GGUF Everything that runs on Mac with 64 GB

Files and context on Mac with 64 GB

Each file of Qwen3.8-Flash-Next-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 64 GB Context (16-bit)Context (8-bit)
Q5_K_M111 GBDoesn't fit——
Q4_K_M94.5 GBDoesn't fit——
IQ4_XS84.9 GBDoesn't fit——

Qwen3.8-Flash-Next-GGUF on other hardware

Popular models that run on Mac with 64 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.