Can I run Qwen3.8-27B-TWIN-TURBO-Fable-Cold-Fusion-709-ULTRA-HERETIC-Uncensored-NM-DAU-NEO-MTP-GGUF on an RTX 5060 Ti 16 GB?

Yes, just

Its IQ2_M file (12.1 GB) fits in the 14.4 GB an RTX 5060 Ti 16 GB can use, with room for ≈ 32K tokens of context. That file is under 3 bits per weight, so expect noticeably lower quality.

ollama run hf.co/DavidAU/Qwen3.8-27B-TWIN-TURBO-Fable-Cold-Fusion-709-ULTRA-HERETIC-Uncensored-NM-DAU-NEO-MTP-GGUF:IQ2_M

Files and context on RTX 5060 Ti 16 GB

Each file of Qwen3.8-27B-TWIN-TURBO-Fable-Cold-Fusion-709-ULTRA-HERETIC-Uncensored-NM-DAU-NEO-MTP-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

Qwen3.8-27B-TWIN-TURBO-Fable-Cold-Fusion-709-ULTRA-HERETIC-Uncensored-NM-DAU-NEO-MTP-GGUF on other hardware

Popular models that run on RTX 5060 Ti 16 GB

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.