Can I run Qwen3.8-40B-Ultimate-Heretic-Uncensored-Turbo-Brilliance-50x-AGI-NEO-GGUF on a Mac with 256 GB?

Yes

Its Q8_0 file (42.0 GB) fits in the 192 GB a Mac with 256 GB can use, with room for ≈ 256K tokens of context.

Full analysis of Qwen3.8-40B-Ultimate-Heretic-Uncensored-Turbo-Brilliance-50x-AGI-NEO-GGUF Everything that runs on Mac with 256 GB Get the Q8_0 file on Hugging Face

ollama run hf.co/DavidAU/Qwen3.8-40B-Ultimate-Heretic-Uncensored-Turbo-Brilliance-50x-AGI-NEO-GGUF:Q8_0

Files and context on Mac with 256 GB

Each file of Qwen3.8-40B-Ultimate-Heretic-Uncensored-Turbo-Brilliance-50x-AGI-NEO-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Mac with 256 GB	Context (16-bit)	Context (8-bit)
Q8_0	42.0 GB	Fits	256K	256K
Q6_K	32.4 GB	Fits	256K	256K
Q5_K_M	28.2 GB	Fits	256K	256K
Q5_K_S	27.3 GB	Fits	256K	256K
Q4_K_M	24.2 GB	Fits	256K	256K
Q4_K_S	22.7 GB	Fits	256K	256K
Qwen3.8-40B-Ultimate-Heretic-Uncn-Turbo-Brilli-50x-AGI-NEO-MTP-IQ4_XS	22.0 GB	Fits	256K	256K
IQ4_XS	21.8 GB	Fits	256K	256K
IQ3_M	18.3 GB	Fits	256K	256K
IQ2_M	14.5 GB	Fits	256K	256K

Qwen3.8-40B-Ultimate-Heretic-Uncensored-Turbo-Brilliance-50x-AGI-NEO-GGUF on other hardware

Popular models that run on Mac with 256 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.