Can I run Edge0-35B-A3B-preview on an RTX 4090?

Yes, just

Its published weights (19.5 GB) fit in the 21.6 GB an RTX 4090 can use, with room for ≈ 97K tokens of context.

hf download Edge0/Edge0-35B-A3B-preview

Files and context on RTX 4090

Each file of Edge0-35B-A3B-preview (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

Edge0-35B-A3B-preview on other hardware

Popular models that run on RTX 4090

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.