Can I run Holo4-27B on an NVIDIA H200?

Yes

Its published weights (54.7 GB) fit in the 127 GB an NVIDIA H200 can use, with room for ≈ 256K tokens of context.

Full analysis of Holo4-27B Everything that runs on NVIDIA H200 Get the weights on Hugging Face

hf download Hcompany/Holo4-27B

Files and context on NVIDIA H200

Each file of Holo4-27B (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On NVIDIA H200	Context (16-bit)	Context (8-bit)
As published	54.7 GB	Fits	256K	256K
Q4_K_MHcompany/Holo4-27B-GGUF	16.9 GB	Fits	256K	256K

Holo4-27B on other hardware

NVIDIA H200Yes
NVIDIA H100Yes
RTX 5090Yes, with a GGUF version
RTX 4090Yes, with a GGUF version
RTX 3090Yes, with a GGUF version
RTX 5060 Ti 16 GBNo
RTX 3060 12 GBNo
RTX 4060No
Mac with 32 GBYes, with a GGUF version
Mac with 64 GBYes, with a GGUF version
Mac with 128 GBYes

Popular models that run on NVIDIA H200

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Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.