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Can I run DeepSeek-V4.1-Flash-1017-GSQ-RCO-GGUF on an NVIDIA H100?

No

Even its smallest file (IQ4_NL, 111 GB) is more than an NVIDIA H100 can hold (72.0 GB usable): it needs 2 of them.

Full analysis of DeepSeek-V4.1-Flash-1017-GSQ-RCO-GGUF Everything that runs on NVIDIA H100

Files and context on NVIDIA H100

Each file of DeepSeek-V4.1-Flash-1017-GSQ-RCO-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn NVIDIA H100 Context (16-bit)Context (8-bit)
IQ2_XS155 GBDoesn't fit——
IQ2_XXS138 GBDoesn't fit——
IQ1_M121 GBDoesn't fit——
IQ4_NL111 GBDoesn't fit——

DeepSeek-V4.1-Flash-1017-GSQ-RCO-GGUF on other hardware

Popular models that run on NVIDIA H100

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.