Can I run Mellum2.1-12B-A2.5B-Thinking on an RTX 5060?

Yes, with a GGUF version

The published weights are too big, but the MXFP4_MOE file from JetBrains/Mellum2.1-12B-A2.5B-Thinking-GGUF (7.03 GB) fits, with room for ≈ 9K tokens of context.

ollama run hf.co/JetBrains/Mellum2.1-12B-A2.5B-Thinking-GGUF:MXFP4_MOE

Files and context on RTX 5060

Each file of Mellum2.1-12B-A2.5B-Thinking (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

Mellum2.1-12B-A2.5B-Thinking on other hardware

Popular models that run on RTX 5060

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.