Can I run Qwen3.8-Flash-Next-oQ4e-mtp on an NVIDIA H100?

No

Even its smallest file (As published, 106 GB) is more than an NVIDIA H100 can hold (72.0 GB usable): it needs 2 of them.

Files and context on NVIDIA H100

Each file of Qwen3.8-Flash-Next-oQ4e-mtp (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

Qwen3.8-Flash-Next-oQ4e-mtp on other hardware

Popular models that run on NVIDIA H100

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.