Can I run Underdog-Saluki-27B-1.0-MTP-Abliterated-GGUF on an RTX 4060?

No

Even its smallest file (Underdog-Saluki-27B-1.0-IQ2-mix-MTP-abliterated, 8.35 GB) is more than an RTX 4060 can hold (7.20 GB usable): it needs 2 of them.

Files and context on RTX 4060

Each file of Underdog-Saluki-27B-1.0-MTP-Abliterated-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

Underdog-Saluki-27B-1.0-MTP-Abliterated-GGUF on other hardware

Popular models that run on RTX 4060

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.