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Can I run d1-2B-GGUF on a Mac with 16 GB?

Yes

Its BF16 file (3.47 GB) fits in the 10.7 GB a Mac with 16 GB can use, with room for ≈ 125K tokens of context.

Full analysis of d1-2B-GGUF Everything that runs on Mac with 16 GB Get the BF16 file on Hugging Face
ollama run hf.co/LiquidAI/d1-2B-GGUF:BF16

Files and context on Mac with 16 GB

Each file of d1-2B-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 16 GB Context (16-bit)Context (8-bit)
BF163.47 GBFits125K125K
F163.47 GBFits125K125K
Q8_01.85 GBFits125K125K
Q4_K_M1.10 GBFits125K125K

d1-2B-GGUF on other hardware

Popular models that run on Mac with 16 GB

Assumes 67% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.