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Can I run d1-omni-600M-GGUF on an NVIDIA B300?

Yes

Its BF16 file (764 MB) fits in the 259 GB an NVIDIA B300 can use, with room for ≈ 125K tokens of context.

Full analysis of d1-omni-600M-GGUF Everything that runs on NVIDIA B300 Get the BF16 file on Hugging Face
ollama run hf.co/LiquidAI/d1-omni-600M-GGUF:BF16

Files and context on NVIDIA B300

Each file of d1-omni-600M-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn NVIDIA B300 Context (16-bit)Context (8-bit)
BF16764 MBFits125K125K
F16764 MBFits125K125K
Q8_0407 MBFits125K125K

d1-omni-600M-GGUF on other hardware

Popular models that run on NVIDIA B300

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.