Can I run Qwen3.6-27B-int4-AutoRound on a Mac with 48 GB?

Yes

Its published weights (19.0 GB) fit in the 36.0 GB a Mac with 48 GB can use, with room for ≈ 251K tokens of context.

Full analysis of Qwen3.6-27B-int4-AutoRound Everything that runs on Mac with 48 GB Get the weights on Hugging Face

hf download Lorbus/Qwen3.6-27B-int4-AutoRound

Files and context on Mac with 48 GB

Each file of Qwen3.6-27B-int4-AutoRound (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Mac with 48 GB	Context (16-bit)	Context (8-bit)
As published	19.0 GB	Fits	251K	256K
4-bit (estimate)	15.6 GB	Fits	256K	256K

Qwen3.6-27B-int4-AutoRound on other hardware

NVIDIA H100Yes
RTX 5090Yes
RTX 4090Yes, just
RTX 3090Yes, just
RTX 5060 Ti 16 GBNo
RTX 3060 12 GBNo
RTX 4060No
Mac with 32 GBYes, just
Mac with 48 GBYes
Mac with 64 GBYes
Mac with 128 GBYes

Popular models that run on Mac with 48 GB

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Qwen3-Coder-30B-A3B-Instruct-GGUFunsloth · 30.5B
Qwen2.5-7B-InstructQwen · 7.62B
Qwen3.5-9BQwen · 9.65B
Qwen2.5-0.5B-InstructQwen · 494M

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.