Can I run Nanbeige4.3-33B-Base on a Mac with 128 GB?

Yes

Its published weights (66.2 GB) fit in the 96.0 GB a Mac with 128 GB can use, with room for ≈ 128K tokens of context.

Full analysis of Nanbeige4.3-33B-Base Everything that runs on Mac with 128 GB Get the weights on Hugging Face

hf download Nanbeige/Nanbeige4.3-33B-Base

Files and context on Mac with 128 GB

Each file of Nanbeige4.3-33B-Base (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Mac with 128 GB	Context (16-bit)	Context (8-bit)
As published	66.2 GB	Fits	128K	128K
4-bit (estimate)	18.6 GB	Fits	128K	128K

Nanbeige4.3-33B-Base on other hardware

NVIDIA H100Yes, just
RTX 5090Probably, at 4-bit
RTX 4090Probably, at 4-bit
RTX 3090Probably, at 4-bit
RTX 5060 Ti 16 GBNo
RTX 3060 12 GBNo
RTX 4060No
Mac with 32 GBProbably, at 4-bit
Mac with 64 GBProbably, at 4-bit
Mac with 128 GBYes

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Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.