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Can I run Arete-27B on a Mac with 192 GB?

Yes

Its published weights (54.7 GB) fit in the 144 GB a Mac with 192 GB can use, with room for ≈ 256K tokens of context.

Full analysis of Arete-27B Everything that runs on Mac with 192 GB Get the weights on Hugging Face
hf download NousResearch/Arete-27B

Files and context on Mac with 192 GB

Each file of Arete-27B (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 192 GB Context (16-bit)Context (8-bit)
As published54.7 GBFits256K256K
BF16bartowski/NousResearch_Arete-27B-GGUF53.8 GBFits256K256K
Q8_0bartowski/NousResearch_Arete-27B-GGUF28.7 GBFits256K256K
Q6_K_Lbartowski/NousResearch_Arete-27B-GGUF24.7 GBFits256K256K
Q6_Kbartowski/NousResearch_Arete-27B-GGUF23.6 GBFits256K256K
Q6_K_Sbartowski/NousResearch_Arete-27B-GGUF22.6 GBFits256K256K
Q5_K_Mbartowski/NousResearch_Arete-27B-GGUF20.7 GBFits256K256K
Q5_K_Sbartowski/NousResearch_Arete-27B-GGUF19.3 GBFits256K256K
Q4_K_Lbartowski/NousResearch_Arete-27B-GGUF18.6 GBFits256K256K
Q4_1bartowski/NousResearch_Arete-27B-GGUF17.6 GBFits256K256K
IQ4_NLbartowski/NousResearch_Arete-27B-GGUF17.2 GBFits256K256K
Q4_K_Mbartowski/NousResearch_Arete-27B-GGUF17.2 GBFits256K256K
Q4_K_Sbartowski/NousResearch_Arete-27B-GGUF16.1 GBFits256K256K
Q4_0bartowski/NousResearch_Arete-27B-GGUF16.1 GBFits256K256K
IQ4_XSbartowski/NousResearch_Arete-27B-GGUF15.2 GBFits256K256K
IQ3_Mbartowski/NousResearch_Arete-27B-GGUF14.6 GBFits256K256K
Q3_K_Lbartowski/NousResearch_Arete-27B-GGUF13.9 GBFits256K256K
Q3_K_Mbartowski/NousResearch_Arete-27B-GGUF13.2 GBFits256K256K
IQ3_XSbartowski/NousResearch_Arete-27B-GGUF12.6 GBFits256K256K
Q3_K_Sbartowski/NousResearch_Arete-27B-GGUF12.5 GBFits256K256K
IQ3_XXSbartowski/NousResearch_Arete-27B-GGUF12.1 GBFits256K256K
Q2_Kbartowski/NousResearch_Arete-27B-GGUF10.6 GBFits256K256K
IQ2_Mbartowski/NousResearch_Arete-27B-GGUF10.3 GBFits256K256K
IQ2_Sbartowski/NousResearch_Arete-27B-GGUF9.45 GBFits256K256K
IQ2_XSbartowski/NousResearch_Arete-27B-GGUF8.85 GBFits256K256K
IQ2_XXSbartowski/NousResearch_Arete-27B-GGUF8.64 GBFits256K256K

Arete-27B on other hardware

Popular models that run on Mac with 192 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.