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Can I run Diplodocus-preview-GGUF on a Radeon RX 7900 XTX?

Yes

Its Q8_0 file (9.57 GB) fits in the 21.6 GB a Radeon RX 7900 XTX can use, with room for ≈ 80K tokens of context.

Full analysis of Diplodocus-preview-GGUF Everything that runs on Radeon RX 7900 XTX Get the Q8_0 file on Hugging Face
ollama run hf.co/OsaurusAI/Diplodocus-preview-GGUF:Q8_0

Files and context on Radeon RX 7900 XTX

Each file of Diplodocus-preview-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Radeon RX 7900 XTX Context (16-bit)Context (8-bit)
Q8_09.57 GBFits80K159K
Q6_K7.76 GBFits92K183K
Q4_K_M6.33 GBFits101K202K

Diplodocus-preview-GGUF on other hardware

Popular models that run on Radeon RX 7900 XTX

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.