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Can I run Qwen2.5-3B-Instruct-AWQ on a Radeon RX 9070 XT?

Yes

Its published weights (2.69 GB) fit in the 14.4 GB a Radeon RX 9070 XT can use, with room for ≈ 32K tokens of context.

Full analysis of Qwen2.5-3B-Instruct-AWQ Everything that runs on Radeon RX 9070 XT Get the weights on Hugging Face
hf download Qwen/Qwen2.5-3B-Instruct-AWQ

Files and context on Radeon RX 9070 XT

Each file of Qwen2.5-3B-Instruct-AWQ (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Radeon RX 9070 XT Context (16-bit)Context (8-bit)
As published2.69 GBFits32K32K
4-bit (estimate)1.91 GBFits32K32K

Qwen2.5-3B-Instruct-AWQ on other hardware

Popular models that run on Radeon RX 9070 XT

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.