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Can I run Qwen3-Next-80B-A3B-Thinking-GGUF on an RTX 3060 12 GB?

No

Even its smallest file (Q4_K_M, 48.4 GB) is more than an RTX 3060 12 GB can hold (10.8 GB usable): it needs 5 of them.

Full analysis of Qwen3-Next-80B-A3B-Thinking-GGUF Everything that runs on RTX 3060 12 GB

Files and context on RTX 3060 12 GB

Each file of Qwen3-Next-80B-A3B-Thinking-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn RTX 3060 12 GB Context (16-bit)Context (8-bit)
Qwen3-Next-80B-A3B-Thinking159 GBDoesn't fit——
Q8_084.8 GBDoesn't fit——
Q6_K65.5 GBDoesn't fit——
Q5_K_M56.7 GBDoesn't fit——
Q5_055.0 GBDoesn't fit——
Q4_K_M48.4 GBDoesn't fit——

Qwen3-Next-80B-A3B-Thinking-GGUF on other hardware

Popular models that run on RTX 3060 12 GB

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.