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Can I run Spark-X2.5-4B-Base on an RTX 6000 Ada?

Yes

Its published weights (8.22 GB) fit in the 43.2 GB an RTX 6000 Ada can use, with room for ≈ 925K tokens of context.

Full analysis of Spark-X2.5-4B-Base Everything that runs on RTX 6000 Ada Get the weights on Hugging Face
hf download XHToken/Spark-X2.5-4B-Base

Files and context on RTX 6000 Ada

Each file of Spark-X2.5-4B-Base (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn RTX 6000 Ada Context (16-bit)Context (8-bit)
As published8.22 GBFits925K1M
4-bit (estimate)2.31 GBFits1M1M

Spark-X2.5-4B-Base on other hardware

Popular models that run on RTX 6000 Ada

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.