Can I run TeleOCR on a Mac with 48 GB?

Yes

Its published weights (2.83 GB) fit in the 36.0 GB a Mac with 48 GB can use, with room for ≈ 125K tokens of context.

hf download XingChen-AGI/TeleOCR

Files and context on Mac with 48 GB

Each file of TeleOCR (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

TeleOCR on other hardware

Popular models that run on Mac with 48 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.