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Can I run Qwen3.8-27B-AP-GGUF on a Mac with 16 GB?

Yes, just

Its IQ2_S file (9.61 GB) fits in the 10.7 GB a Mac with 16 GB can use, with room for ≈ 13K tokens of context. That file is under 3 bits per weight, so expect noticeably lower quality.

Full analysis of Qwen3.8-27B-AP-GGUF Everything that runs on Mac with 16 GB Get the IQ2_S file on Hugging Face
ollama run hf.co/agentionai/Qwen3.8-27B-AP-GGUF:IQ2_S

Files and context on Mac with 16 GB

Each file of Qwen3.8-27B-AP-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 16 GB Context (16-bit)Context (8-bit)
Q4_K_XL17.6 GBDoesn't fit——
Q4_K_M16.5 GBDoesn't fit——
IQ4_XS14.3 GBDoesn't fit——
Q3_K_XL13.1 GBDoesn't fit——
IQ3_S12.0 GBDoesn't fit——
IQ3_XS11.5 GBDoesn't fit——
IQ3_XXS10.7 GBDoesn't fit——
IQ2_S9.61 GBTight13K27K

Qwen3.8-27B-AP-GGUF on other hardware

Popular models that run on Mac with 16 GB

Assumes 67% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.