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Can I run Qwen3.8-27B-DSpine-b16-GGUF on a Radeon RX 7900 XTX?

Yes

Its BF16 file (4.06 GB) fits in the 21.6 GB a Radeon RX 7900 XTX can use, with room for ≈ 256K tokens of context.

Full analysis of Qwen3.8-27B-DSpine-b16-GGUF Everything that runs on Radeon RX 7900 XTX Get the BF16 file on Hugging Face
ollama run hf.co/aj9o9/Qwen3.8-27B-DSpine-b16-GGUF:BF16

Files and context on Radeon RX 7900 XTX

Each file of Qwen3.8-27B-DSpine-b16-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Radeon RX 7900 XTX Context (16-bit)Context (8-bit)
BF164.06 GBFits256K256K
Q8_02.20 GBFits256K256K
Q4_K_M1.26 GBFits256K256K

Qwen3.8-27B-DSpine-b16-GGUF on other hardware

Popular models that run on Radeon RX 7900 XTX

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.