Can I run GLM-5.3-Flash-GGUF-DGX-Spark on a Mac with 192 GB?

Yes

Its GLM-5.3-Flash-Q2-DGX-Spark file (84.9 GB) fits in the 144 GB a Mac with 192 GB can use, with room for an unknown amount of context.

llama-server -hf autotrust/GLM-5.3-Flash-GGUF-DGX-Spark

Files and context on Mac with 192 GB

Each file of GLM-5.3-Flash-GGUF-DGX-Spark (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

GLM-5.3-Flash-GGUF-DGX-Spark on other hardware

Popular models that run on Mac with 192 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.