Can I run flux-3-image-klein-pup on a Mac with 256 GB?

Yes

Its published weights (18.8 GB) fit in the 192 GB a Mac with 256 GB can use, with room for ≈ 256K tokens of context.

Full analysis of flux-3-image-klein-pup Everything that runs on Mac with 256 GB Get the weights on Hugging Face

hf download black-forest-labs/flux-3-image-klein-pup

Files and context on Mac with 256 GB

Each file of flux-3-image-klein-pup (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Mac with 256 GB	Context (16-bit)	Context (8-bit)
As published	18.8 GB	Fits	256K	256K
4-bit (estimate)	5.29 GB	Fits	256K	256K

flux-3-image-klein-pup on other hardware

NVIDIA H100Yes
RTX 5090Yes
RTX 4090Yes, just
RTX 3090Yes, just
RTX 5060 Ti 16 GBProbably, at 4-bit
RTX 3060 12 GBProbably, at 4-bit
RTX 4060Probably, at 4-bit
Mac with 32 GBYes, just
Mac with 64 GBYes
Mac with 128 GBYes
Mac with 256 GBYes

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Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.