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Can I run Nanbeige4.3-33B-UNCENSORED-GGUF on a Mac with 64 GB?

Yes

Its Q6_K file (27.2 GB) fits in the 48.0 GB a Mac with 64 GB can use, with room for ≈ 95K tokens of context.

Full analysis of Nanbeige4.3-33B-UNCENSORED-GGUF Everything that runs on Mac with 64 GB Get the Q6_K file on Hugging Face
ollama run hf.co/dealignai/Nanbeige4.3-33B-UNCENSORED-GGUF:Q6_K

Files and context on Mac with 64 GB

Each file of Nanbeige4.3-33B-UNCENSORED-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 64 GB Context (16-bit)Context (8-bit)
Q6_K27.2 GBFits95K191K
Q4_K_M20.1 GBFits128K256K
IQ2_XXS9.33 GBFits177K355K

Nanbeige4.3-33B-UNCENSORED-GGUF on other hardware

Popular models that run on Mac with 64 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.