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Can I run Qwen3.8-9B-Distill-GGUF on an RTX 4080?

Yes

Its Q8_0 file (9.79 GB) fits in the 14.4 GB an RTX 4080 can use, with room for ≈ 136K tokens of context.

Full analysis of Qwen3.8-9B-Distill-GGUF Everything that runs on RTX 4080 Get the Q8_0 file on Hugging Face
ollama run hf.co/empero-ai/Qwen3.8-9B-Distill-GGUF:Q8_0

Files and context on RTX 4080

Each file of Qwen3.8-9B-Distill-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn RTX 4080 Context (16-bit)Context (8-bit)
BF1618.4 GBDoesn't fit——
Q8_09.79 GBFits136K256K
Q6_K7.56 GBFits202K256K
Q5_K_M6.64 GBFits230K256K
Q4_K_M5.78 GBFits255K256K

Qwen3.8-9B-Distill-GGUF on other hardware

Popular models that run on RTX 4080

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.