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Can I run Qwythos-9B-Claude-Mythos-5-1M-GGUF on an RTX 5090?

Yes

Its Qwythos-9B-Claude-Mythos-5-1M-MTP-BF16 file (18.4 GB) fits in the 28.8 GB an RTX 5090 can use, with room for ≈ 308K tokens of context.

Full analysis of Qwythos-9B-Claude-Mythos-5-1M-GGUF Everything that runs on RTX 5090 Get the Qwythos-9B-Claude-Mythos-5-1M-MTP-BF16 file on Hugging Face
ollama run hf.co/empero-ai/Qwythos-9B-Claude-Mythos-5-1M-GGUF

Files and context on RTX 5090

Each file of Qwythos-9B-Claude-Mythos-5-1M-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn RTX 5090 Context (16-bit)Context (8-bit)
Qwythos-9B-Claude-Mythos-5-1M-MTP-BF1618.4 GBFits308K616K
BF1617.9 GBFits323K645K
Q8_09.79 GBFits565K1M
Qwythos-9B-Claude-Mythos-5-1M-Q8_09.53 GBFits573K1M
Q6_K7.62 GBFits630K1M
Qwythos-9B-Claude-Mythos-5-1M-Q6_K7.36 GBFits637K1M
Q5_K_M6.73 GBFits656K1M
Qwythos-9B-Claude-Mythos-5-1M-Q5_K_M6.47 GBFits664K1M
Q4_K_M5.89 GBFits681K1M
Qwythos-9B-Claude-Mythos-5-1M-Q4_K_M5.63 GBFits689K1M

Qwythos-9B-Claude-Mythos-5-1M-GGUF on other hardware

Popular models that run on RTX 5090

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.