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Can I run OpenJev-GGUF on a Mac with 48 GB?

Yes

Its Q8_0 file (28.6 GB) fits in the 36.0 GB a Mac with 48 GB can use, with room for ≈ 108K tokens of context.

Full analysis of OpenJev-GGUF Everything that runs on Mac with 48 GB Get the Q8_0 file on Hugging Face
ollama run hf.co/ggml-org/OpenJev-GGUF:Q8_0

Files and context on Mac with 48 GB

Each file of OpenJev-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 48 GB Context (16-bit)Context (8-bit)
BF1653.8 GBDoesn't fit——
Q8_028.6 GBFits108K216K
Q4_K_M19.0 GBFits251K256K

OpenJev-GGUF on other hardware

Popular models that run on Mac with 48 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.