Can I run gemma-4-26B-A4B-it on an RTX 5060 Ti 16 GB?

Yes, with a GGUF version

The published weights are too big, but the UD-IQ4_NL file from unsloth/gemma-4-26B-A4B-it-GGUF (13.6 GB) fits, with room for ≈ 4K tokens of context.

ollama run hf.co/unsloth/gemma-4-26B-A4B-it-GGUF:UD-IQ4_NL

Files and context on RTX 5060 Ti 16 GB

Each file of gemma-4-26B-A4B-it (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

gemma-4-26B-A4B-it on other hardware

Popular models that run on RTX 5060 Ti 16 GB

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.