Can I run gemma-4-26B-A4B on an NVIDIA B200?

Yes

Its published weights (51.6 GB) fit in the 162 GB an NVIDIA B200 can use, with room for ≈ 256K tokens of context.

Full analysis of gemma-4-26B-A4B Everything that runs on NVIDIA B200 Get the weights on Hugging Face

hf download google/gemma-4-26B-A4B

Files and context on NVIDIA B200

Each file of gemma-4-26B-A4B (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On NVIDIA B200	Context (16-bit)	Context (8-bit)
As published	51.6 GB	Fits	256K	256K
4-bit (estimate)	14.5 GB	Fits	256K	256K

gemma-4-26B-A4B on other hardware

NVIDIA B200Yes
NVIDIA H100Yes
RTX 5090Probably, at 4-bit
RTX 4090Probably, at 4-bit
RTX 3090Probably, at 4-bit
RTX 5060 Ti 16 GBNo
RTX 3060 12 GBNo
RTX 4060No
Mac with 32 GBProbably, at 4-bit
Mac with 64 GBProbably, at 4-bit
Mac with 128 GBYes

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Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.