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Can I run Tess-4.5-27B-GGUF on a Mac with 32 GB?

Yes

Its Q4_K_M file (16.5 GB) fits in the 21.3 GB a Mac with 32 GB can use, with room for ≈ 69K tokens of context.

Full analysis of Tess-4.5-27B-GGUF Everything that runs on Mac with 32 GB Get the Q4_K_M file on Hugging Face
ollama run hf.co/migtissera/Tess-4.5-27B-GGUF:Q4_K_M

Files and context on Mac with 32 GB

Each file of Tess-4.5-27B-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 32 GB Context (16-bit)Context (8-bit)
Q8_028.6 GBDoesn't fit——
Q6_K22.1 GBDoesn't fit——
Q4_K_M16.5 GBFits69K138K

Tess-4.5-27B-GGUF on other hardware

Popular models that run on Mac with 32 GB

Assumes 67% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.