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Can I run Ornith-1.5-397B-GGUF on a Mac with 128 GB?

No

Even its smallest file (Q4_K_M, 244 GB) is more than a Mac with 128 GB can hold (96.0 GB usable): it needs a Mac with 512 GB.

Full analysis of Ornith-1.5-397B-GGUF Everything that runs on Mac with 128 GB

Files and context on Mac with 128 GB

Each file of Ornith-1.5-397B-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 128 GB Context (16-bit)Context (8-bit)
Q8_0429 GBDoesn't fit——
Q6_K331 GBDoesn't fit——
Q5_K_M286 GBDoesn't fit——
Q4_K_M244 GBDoesn't fit——

Ornith-1.5-397B-GGUF on other hardware

Popular models that run on Mac with 128 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.