Can I run Laguna-S-2.1 on a Mac with 64 GB?

Even its smallest file (4-bit (estimate), 66.1 GB) is more than a Mac with 64 GB can hold (48.0 GB usable): it needs a Mac with 96 GB.

Full analysis of Laguna-S-2.1 Everything that runs on Mac with 64 GB

Files and context on Mac with 64 GB

Each file of Laguna-S-2.1 (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Mac with 64 GB	Context (16-bit)	Context (8-bit)
As published	235 GB	Doesn't fit	—	—
4-bit (estimate)	66.1 GB	Doesn't fit	—	—

Laguna-S-2.1 on other hardware

NVIDIA H100Probably, at 4-bit
RTX 5090No
RTX 4090No
RTX 3090No
RTX 5060 Ti 16 GBNo
RTX 3060 12 GBNo
RTX 4060No
Mac with 32 GBNo
Mac with 64 GBNo
Mac with 128 GBProbably, at 4-bit

Popular models that run on Mac with 64 GB

Qwen3-0.6BQwen · 752M
Qwen3-VL-8B-InstructQwen · 8.77B
gpt2openai-community · 137M
Qwen3-8BQwen · 8.19B
Qwen3-Coder-30B-A3B-Instruct-GGUFunsloth · 30.5B
Qwen2.5-7B-InstructQwen · 7.62B
Qwen3.5-9BQwen · 9.65B
Qwen2.5-0.5B-InstructQwen · 494M

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.