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Can I run Bonsai-27B-gguf on an NVIDIA B300?

Yes

Its F16 file (53.8 GB) fits in the 259 GB an NVIDIA B300 can use, with room for ≈ 4K tokens of context.

Full analysis of Bonsai-27B-gguf Everything that runs on NVIDIA B300 Get the F16 file on Hugging Face
ollama run hf.co/prism-ml/Bonsai-27B-gguf:F16

Files and context on NVIDIA B300

Each file of Bonsai-27B-gguf (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn NVIDIA B300 Context (16-bit)Context (8-bit)
F1653.8 GBFits4K4K
BF167.29 GBFits4K4K
Bonsai-27B-Q1_03.80 GBFits4K4K
Q4_11.79 GBFits4K4K

Bonsai-27B-gguf on other hardware

Popular models that run on NVIDIA B300

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.