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Can I run Ternary-Bonsai-27B-gguf on a Mac with 64 GB?

Yes

Its Ternary-Bonsai-27B-Q2_g64 file (7.59 GB) fits in the 48.0 GB a Mac with 64 GB can use, with room for ≈ 4K tokens of context.

Full analysis of Ternary-Bonsai-27B-gguf Everything that runs on Mac with 64 GB Get the Ternary-Bonsai-27B-Q2_g64 file on Hugging Face
ollama run hf.co/prism-ml/Ternary-Bonsai-27B-gguf

Files and context on Mac with 64 GB

Each file of Ternary-Bonsai-27B-gguf (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 64 GB Context (16-bit)Context (8-bit)
F1653.8 GBDoesn't fit——
Ternary-Bonsai-27B-Q2_g647.59 GBFits4K4K
BF167.29 GBFits4K4K
Ternary-Bonsai-27B-PQ2_07.17 GBFits4K4K
Ternary-Bonsai-27B-Q2_07.17 GBFits4K4K
Q4_11.95 GBFits4K4K

Ternary-Bonsai-27B-gguf on other hardware

Popular models that run on Mac with 64 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.