Can I run MNN-Pocket-0.3B on a Mac with 48 GB?

Yes

Its published weights (723 MB) fit in the 36.0 GB a Mac with 48 GB can use, with room for ≈ 40K tokens of context.

Full analysis of MNN-Pocket-0.3B Everything that runs on Mac with 48 GB Get the weights on Hugging Face

hf download taobao-mnn/MNN-Pocket-0.3B

Files and context on Mac with 48 GB

Each file of MNN-Pocket-0.3B (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Mac with 48 GB	Context (16-bit)	Context (8-bit)
As published	723 MB	Fits	40K	40K
4-bit (estimate)	203 MB	Fits	40K	40K

MNN-Pocket-0.3B on other hardware

NVIDIA H100Yes
RTX 5090Yes
RTX 4090Yes
RTX 3090Yes
RTX 5060 Ti 16 GBYes
RTX 3060 12 GBYes
RTX 4060Yes
Mac with 32 GBYes
Mac with 48 GBYes
Mac with 64 GBYes
Mac with 128 GBYes

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Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.