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Can I run HunyuanOCR on a Radeon RX 7900 XTX?

Yes

Its published weights (2.24 GB) fit in the 21.6 GB a Radeon RX 7900 XTX can use, with room for ≈ 128K tokens of context.

Full analysis of HunyuanOCR Everything that runs on Radeon RX 7900 XTX Get the weights on Hugging Face
hf download tencent/HunyuanOCR

Files and context on Radeon RX 7900 XTX

Each file of HunyuanOCR (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Radeon RX 7900 XTX Context (16-bit)Context (8-bit)
As published2.24 GBFits128K128K
4-bit (estimate)630 MBFits128K128K

HunyuanOCR on other hardware

Popular models that run on Radeon RX 7900 XTX

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.