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Can I run Qwen3.8-27B-DSpine-b16 on a Mac with 32 GB?

Yes

Its published weights (4.05 GB) fit in the 21.3 GB a Mac with 32 GB can use, with room for ≈ 256K tokens of context.

Full analysis of Qwen3.8-27B-DSpine-b16 Everything that runs on Mac with 32 GB Get the weights on Hugging Face
hf download tencent/Qwen3.8-27B-DSpine-b16

Files and context on Mac with 32 GB

Each file of Qwen3.8-27B-DSpine-b16 (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 32 GB Context (16-bit)Context (8-bit)
As published4.05 GBFits256K256K
BF16aj9o9/Qwen3.8-27B-DSpine-b16-GGUF4.06 GBFits256K256K
Q8_0aj9o9/Qwen3.8-27B-DSpine-b16-GGUF2.20 GBFits256K256K
Q4_K_Maj9o9/Qwen3.8-27B-DSpine-b16-GGUF1.26 GBFits256K256K

Qwen3.8-27B-DSpine-b16 on other hardware

Popular models that run on Mac with 32 GB

Assumes 67% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.