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Can I run GLM-5.3-Flash-GGUF on a Mac with 256 GB?

Yes

Its UD-Q3_K_XL file (148 GB) fits in the 192 GB a Mac with 256 GB can use, with room for an unknown amount of context.

Full analysis of GLM-5.3-Flash-GGUF Everything that runs on Mac with 256 GB Get the UD-Q3_K_XL file on Hugging Face
llama-server -hf unsloth/GLM-5.3-Flash-GGUF:UD-Q3_K_XL

Files and context on Mac with 256 GB

Each file of GLM-5.3-Flash-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 256 GB Context (16-bit)Context (8-bit)
BF16642 GBDoesn't fit——
Q8_0341 GBDoesn't fit——
UD-Q6_K_XL292 GBDoesn't fit——
UD-Q5_K_XL240 GBDoesn't fit——
UD-Q4_K_XL200 GBDoesn't fit——
UD-IQ4_XS157 GBDoesn't fit——
UD-Q3_K_XL148 GBFitsnot knownnot known
UD-IQ3_XXS120 GBFitsnot knownnot known
UD-Q2_K_XL109 GBFitsnot knownnot known
UD-IQ2_XXS102 GBFitsnot knownnot known
UD-IQ1_M97.6 GBFitsnot knownnot known
UD-IQ1_S93.1 GBFitsnot knownnot known

GLM-5.3-Flash-GGUF on other hardware

Popular models that run on Mac with 256 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.