Can I run Inkling-Small-GGUF on a Mac with 64 GB?

No

Even its smallest file (UD-IQ1_S, 74.8 GB) is more than a Mac with 64 GB can hold (48.0 GB usable): it needs a Mac with 128 GB.

Files and context on Mac with 64 GB

Each file of Inkling-Small-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

Inkling-Small-GGUF on other hardware

Popular models that run on Mac with 64 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.