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Can I run Qwen3.6-27B-GGUF on an RTX 4090?

Yes, just

Its UD-Q5_K_XL file (20.0 GB) fits in the 21.6 GB an RTX 4090 can use, with room for ≈ 21K tokens of context.

Full analysis of Qwen3.6-27B-GGUF Everything that runs on RTX 4090 Get the UD-Q5_K_XL file on Hugging Face
ollama run hf.co/unsloth/Qwen3.6-27B-GGUF:UD-Q5_K_XL

Files and context on RTX 4090

Each file of Qwen3.6-27B-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn RTX 4090 Context (16-bit)Context (8-bit)
BF1653.8 GBDoesn't fit——
UD-Q8_K_XL35.3 GBDoesn't fit——
Q8_028.6 GBDoesn't fit——
UD-Q6_K_XL25.6 GBDoesn't fit——
Q6_K22.5 GBDoesn't fit——
UD-Q5_K_XL20.0 GBTight21K42K
Q5_K_M19.5 GBTight29K58K
Q5_K_S19.0 GBTight37K74K
UD-Q4_K_XL17.6 GBTight57K114K
Q4_117.3 GBFits62K125K
Q4_K_M16.8 GBFits69K138K
IQ4_NL16.1 GBFits80K160K
Q4_K_S15.9 GBFits83K167K
Q4_015.8 GBFits84K169K
IQ4_XS15.4 GBFits89K179K
UD-Q3_K_XL14.5 GBFits104K208K
Q3_K_M13.6 GBFits117K234K
Q3_K_S12.4 GBFits135K256K
UD-IQ3_XXS12.0 GBFits141K256K
UD-Q2_K_XL11.8 GBFits143K256K
UD-IQ2_M10.8 GBFits158K256K
UD-IQ2_XXS9.39 GBFits180K256K

Qwen3.6-27B-GGUF on other hardware

Popular models that run on RTX 4090

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.