Can I run gemma-4-12B-agentic-fable5-composer2.5-v2-3.5x-tau2-GGUF on a Mac with 64 GB?

Yes

Its gemma4-v2-Q8_0 file (12.7 GB) fits in the 48.0 GB a Mac with 64 GB can use, with room for ≈ 256K tokens of context.

Full analysis of gemma-4-12B-agentic-fable5-composer2.5-v2-3.5x-tau2-GGUF Everything that runs on Mac with 64 GB Get the gemma4-v2-Q8_0 file on Hugging Face

ollama run hf.co/yuxinlu1/gemma-4-12B-agentic-fable5-composer2.5-v2-3.5x-tau2-GGUF

Files and context on Mac with 64 GB

Each file of gemma-4-12B-agentic-fable5-composer2.5-v2-3.5x-tau2-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Mac with 64 GB	Context (16-bit)	Context (8-bit)
gemma4-v2-Q8_0	12.7 GB	Fits	256K	256K
Q6_K	9.79 GB	Fits	256K	256K
Q4_K_M	7.38 GB	Fits	256K	256K
Q3_K_M	6.09 GB	Fits	256K	256K

gemma-4-12B-agentic-fable5-composer2.5-v2-3.5x-tau2-GGUF on other hardware

Popular models that run on Mac with 64 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.