Can I run Qwen3-VL-4B-Instruct on a Radeon RX 7900 XTX?

Yes

Its published weights (8.88 GB) fit in the 21.6 GB a Radeon RX 7900 XTX can use, with room for ≈ 84K tokens of context.

Full analysis of Qwen3-VL-4B-Instruct Everything that runs on Radeon RX 7900 XTX Get the weights on Hugging Face

hf download Qwen/Qwen3-VL-4B-Instruct

Files and context on Radeon RX 7900 XTX

Each file of Qwen3-VL-4B-Instruct (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On Radeon RX 7900 XTX	Context (16-bit)	Context (8-bit)
As published	8.88 GB	Fits	84K	169K
F16Qwen/Qwen3-VL-4B-Instruct-GGUF	8.05 GB	Fits	90K	179K
Q8_0Qwen/Qwen3-VL-4B-Instruct-GGUF	4.28 GB	Fits	115K	229K
Q4_K_MQwen/Qwen3-VL-4B-Instruct-GGUF	2.50 GB	Fits	127K	253K

Qwen3-VL-4B-Instruct on other hardware

Popular models that run on Radeon RX 7900 XTX

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.