Can I run blip2-opt-2.7b on an RTX PRO 6000 Blackwell?

Yes

Its published weights (15.0 GB) fit in the 86.4 GB an RTX PRO 6000 Blackwell can use, with room for ≈ 213K tokens of context.

hf download Salesforce/blip2-opt-2.7b

Files and context on RTX PRO 6000 Blackwell

Each file of blip2-opt-2.7b (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

blip2-opt-2.7b on other hardware

Popular models that run on RTX PRO 6000 Blackwell

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.