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Can I run GLM-5.3-Flash on a Mac with 512 GB?

Yes, just

Its published weights (328 GB) fit in the 384 GB a Mac with 512 GB can use, with room for ≈ 1M tokens of context.

Full analysis of GLM-5.3-Flash Everything that runs on Mac with 512 GB Get the weights on Hugging Face
hf download zai-org/GLM-5.3-Flash

Files and context on Mac with 512 GB

Each file of GLM-5.3-Flash (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

FileSizeOn Mac with 512 GB Context (16-bit)Context (8-bit)
As published328 GBTight1M1M
BF16unsloth/GLM-5.3-Flash-GGUF642 GBDoesn't fit——
Q8_0unsloth/GLM-5.3-Flash-GGUF341 GBDoesn't fit——
UD-Q6_K_XLunsloth/GLM-5.3-Flash-GGUF292 GBFitsnot knownnot known
UD-Q5_K_XLunsloth/GLM-5.3-Flash-GGUF240 GBFitsnot knownnot known
UD-Q4_K_XLunsloth/GLM-5.3-Flash-GGUF200 GBFitsnot knownnot known
UD-IQ4_XSunsloth/GLM-5.3-Flash-GGUF157 GBFitsnot knownnot known
UD-Q3_K_XLunsloth/GLM-5.3-Flash-GGUF148 GBFitsnot knownnot known
UD-IQ3_XXSunsloth/GLM-5.3-Flash-GGUF120 GBFitsnot knownnot known
UD-Q2_K_XLunsloth/GLM-5.3-Flash-GGUF109 GBFitsnot knownnot known
UD-IQ2_XXSunsloth/GLM-5.3-Flash-GGUF102 GBFitsnot knownnot known
UD-IQ1_Munsloth/GLM-5.3-Flash-GGUF97.6 GBFitsnot knownnot known
UD-IQ1_Sunsloth/GLM-5.3-Flash-GGUF93.1 GBFitsnot knownnot known

GLM-5.3-Flash on other hardware

Popular models that run on Mac with 512 GB

Assumes 75% of the Mac's memory is usable (macOS's default limit for the GPU; it can be raised) and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.