Can I run Signal-3.8-27B-GGUF on an RTX 5090?

Yes

Its Q6_K file (22.4 GB) fits in the 28.8 GB an RTX 5090 can use, with room for ≈ 93K tokens of context.

Full analysis of Signal-3.8-27B-GGUF Everything that runs on RTX 5090 Get the Q6_K file on Hugging Face

ollama run hf.co/agentionai/Signal-3.8-27B-GGUF:Q6_K

Files and context on RTX 5090

Each file of Signal-3.8-27B-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On RTX 5090	Context (16-bit)	Context (8-bit)
Q8_0	29.0 GB	Doesn't fit	—	—
Q6_K	22.4 GB	Fits	93K	185K
Q5_K_M	19.5 GB	Fits	136K	256K
Q4_K_XL	17.6 GB	Fits	165K	256K
Q4_K_M	17.0 GB	Fits	174K	256K
Q3_K_XL	15.1 GB	Fits	202K	256K
IQ4_XS	14.3 GB	Fits	214K	256K
IQ3_S	13.3 GB	Fits	229K	256K
IQ3_XXS	12.2 GB	Fits	245K	256K

Signal-3.8-27B-GGUF on other hardware

Popular models that run on RTX 5090

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.