Can I run Signal-3.8-27B-GGUF on an RTX PRO 6000 Blackwell?

Yes

Its Q8_0 file (29.0 GB) fits in the 86.4 GB an RTX PRO 6000 Blackwell can use, with room for ≈ 256K tokens of context.

Full analysis of Signal-3.8-27B-GGUF Everything that runs on RTX PRO 6000 Blackwell Get the Q8_0 file on Hugging Face

ollama run hf.co/agentionai/Signal-3.8-27B-GGUF:Q8_0

Files and context on RTX PRO 6000 Blackwell

Each file of Signal-3.8-27B-GGUF (and of GGUF versions the site has analyzed), and how much context fits next to it, with the context cache in 16-bit or 8-bit.

File	Size	On RTX PRO 6000 Blackwell	Context (16-bit)	Context (8-bit)
Q8_0	29.0 GB	Fits	256K	256K
Q6_K	22.4 GB	Fits	256K	256K
Q5_K_M	19.5 GB	Fits	256K	256K
Q4_K_XL	17.6 GB	Fits	256K	256K
Q4_K_M	17.0 GB	Fits	256K	256K
Q3_K_XL	15.1 GB	Fits	256K	256K
IQ4_XS	14.3 GB	Fits	256K	256K
IQ3_S	13.3 GB	Fits	256K	256K
IQ3_XXS	12.2 GB	Fits	256K	256K

Signal-3.8-27B-GGUF on other hardware

Popular models that run on RTX PRO 6000 Blackwell

Assumes 90% of the card's memory is usable and at least 4K tokens of context for one conversation, with the context cache in 16-bit unless noted. Fits leaves at least 20% of that memory for context; Tight leaves less.